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An ISUOG Advanced Course
Hot topics & controversies in feto-maternal medicine
3rd edition


Thursday 24th November 2022

13.00 Registration

14.00 Course Opening

CNS I. From screening standards to corpus callosum dysraphic states. Time for debate.
Chairs: Roee Birnbaum, Dario Paladini

14.10 A creative approach to the CNS screening views: bullhorns and butterflies.
Guillermo Azumendi
14.30 LIVE DEMO 1. The…bullhorns and butterflies…on the screen. Rabih Chaoui
Corpus callosum dysraphic states. Is there a terminology issue? Laurent J. Salomon
Corpus callosum agenesis. From suspicion to diagnosis and associations. Dario Paladini
15.30 CSP agenesis. From suspicion to diagnosis and associations. Paolo Volpe
Debate & voting. Midsagittal view in screening / Short corpus callosum: is there such an entity? Faculty televoter session 1 & discussion

16.10   Coffee Break

CNS II. Late onset anomalies
Chairs: Roee Birnbaum
, Paolo Volpe

16.40 LIVE DEMO 2. The late neurosonography. Paolo Volpe
17.00 Intra-ventricular hemorrhage and stroke.Dario Paladini
17.20 Endocranial cysts. Classification, significance and prognosis. Rabih Chaoui
17.40 Pericallosal lipomas. Diagnosis and significance. Roee Birnbaum
18.00 The role of prenatal MRI in acquired lesions. Maria Savino Severino

18.20 Discussion

18.40 End of the day

Friday 25th November 2022

Soft markers in the 2nd trimester: a legacy from the past…to get rid of in the era of cf-DNA and FTS?
Chairs: Dario Paladini, Paolo Volpe
08.30 Introduction to the topic. Rationale and endpoints. Dario Paladini
08.45 Choroid plexus cysts. Dario Paladini
09.00 Absent nasal bone. Marisa Borenstein 
09.15 ARSARabih Chaoui
09.30 Cardiac hyperechogenic foci.Roee Birnbaum
09.45 Hyperechogenic bowel. Laurent J. Salomon
10.00 Single umbilical artery. Paolo Volpe
Televoter 2 & discussion

10.45   Coffee Break

Hot topics in fetomaternal medicine. 1. Diabetes in pregnancy. Point of Care.
Chairs: Tiziana Frusca, Pasquale Martinelli

11.15 National and international guidelines for screening and diagnosis. Federico Mecacci
11.35 The metabolic background and the role of metformin and inositol supplementation. Irene Cetin
11.55 Clinical and delivery challenges. Tiziana Frusca
12.15 LIVE DEMO 3. How to scan and what to check.
Fetal ultrasound surveillance Laurent J. Salomon

12.40 Discussion

13.00 Lunch
Lunch Symposium GE (No ECM)
Ultra-resolution in fetal imaging: You Set The Limits
13.15  New frontiers of high resolution in the characterization of the fetal anatomy 
13.30  Benefits of new technologies in the 12-13 weeks anatomic assessment 

14.30 – 16.10
Ready player 1? Artificial intelligence in obstetric ultrasound: commercially available and investigational tools.
Chairs: Dario Paladini, Federico Prefumo

14.30 AI-aided anomaly scan. A step forward. Hongning Xie
14.50 New tools in AI-aided obstetric ultrasound. Aris Papagheorghiou
15.10 Automatic 3D fetal facial dysmorphology algorithm. Christoph Lees
15.30 New portable transducers. Federico Prefumo

15.50 Discussion

16.10   Coffee Break

Symposium Perkin Elmer (No ECM)
A new approach to NIPT screening
Introduction PE Massimiliano Franchi
Introduction NIPT Vanadis System Riccardo Piona
Evaluation of a simplified cfDNA screening method for common autosomal trisomies Geralyn Lambert-Messerlian

17.30 – 18.30
When experience is not enough. The malformation cases that remind us to be humble in making a diagnosis/prognosis…
Chairs: Rabih Chaoui, Dario Paladini

17.30 Shared Experiences Rabih Chaoui
17.45 Shared Experiences Dario Paladini
18.00 Shared Experiences Paolo Volpe

18.15 Discussion

18.30 End of the day

Saturday 26th November 2022

Hot topics in fetomaternal medicine. 2. Challenges in the management of the small fetus.
Chairs: Tiziana Frusca, Dario Paladini
08.30 What biometry charts should I use? The PROs of the Intergrowth study. Aris Papagheorghiou
08.50 What biometry charts should I use?  The CONs of the Intergrowth study. Tamara Stampaljia
09.20 How to diagnose and manage growth-restriction. Still a controversial issue. Christoph Lees
09.50 The neonatologist’s point of view. Luca Ramenghi
10.10  Discussion & voting

10.30  Coffee break

Congenital heart disease. What do we miss and why…a methodological analysis of FPs and FNs.
Chairs: Maurizio Marasini, Fabrizio Taddei

11.15 LIVE DEMO 4.New technologies, FP and FN Dario Paladini
11.35 Malalignment and VA connections. Rabih Chaoui
11.55 Cardiac septa. Valentina De Robertis
12.15 Ventricular disproportion.  Paolo Volpe
12.35 Single ventricle anatomy Giulia Tuo

12.55 Discussion

13.15 CME test and goodbye

Prof. Dario Paladini

Course Objective

The third edition of the course has three components.

The first part focuses on the sonographic expert diagnosis of complex CNS and cardiac malformations, concentrating especially on those anomalies or sonographic aspects that may be responsible for false positive and negative diagnoses.

The second part addresses the modifications of current diagnostic ultrasound protocols that should be implemented thanks to the new advancements in genetics and Artificial Intelligence.

The third part deals – as  in previous editions – with feto-maternal important conditions, which in the present edition is maternal diabetes and its effects on the pregnancy and the fetus.

A final session is included focusing on the state of the art in the hormonal treatment of women’s conditions.

Invited Faculty

Guilllermo Azumendi (Malaga, Spain)
Roee Birnbaum (Tel Aviv, Israel)
Marisa Borenstein (Malaga, Spain)

Irene Cetin (Milano)
Rabih Chaoui (Berlin, Germany)
Valentina De Robertis (Bari)
Tiziana Frusca (Brescia)
Christoph Lees (London, UK)
Maurizio Marasini (Genova)
Pasquale Martinelli (Napoli)
Federico Mecacci (Firenze) 
Giovanni Monni (Cagliari)
Dario Paladini (Genova)
Aris Papagheorghiou (Oxford, UK)
Federico Prefumo (Genova)

Luca Ramenghi (Genova)
Laurent J. Salomon (Paris, France)
Maria Savina Severino (Genova)

Tamara Stampaljia (Trieste)
Fabrizio Taddei (Rovereto)
Giulia Tuo (Genova)
Paolo Volpe (Bari)
Hongning Xie (Guangzhou, China)

General Information

Congress Venue
Magazzini del Cotone

Via Magazzini del Cotone, 19
16128 Genova (Italy)

Security measures
In accordance with the regulations in force on the date of the conference, all due measures for the containment and management of the Covid-19 emergency will be put in place to protect attendees and staff throughout the event.

Official language
English is the official language of the Congress. Simultaneous translation into Italian will be available.

Scientific Information

Course Directors

Prof. Dario Paladini, MD
Head, Fetal Medicine & Surgery Unit
G. Gaslini Institute, Genova, Italy

Scientific Secretariat
D. Paladini, D. Buffi, I. Maffeo, D. Pastorino, C. Scala

UOSD di Medicina e Chirurgia Fetale
IRCCS G. Gaslini

L.go Gerolamo Gaslini, 5
16147 Genova, Italy
Tel 010 56363483

E-mail: dpaladini49@gmail.com


The Organizing Secretariat can reserve hotel accommodation for

2 nights

Check-in: 24 November 2022

Check-out: 26 November 2022

at the following hotels:

  • NH Collection Marina ★★★★
    Molo Ponte Calvi 5, 16124 Genova – Tel +39 010 25391
  • NH Genova Centro ★★★★
    Via Martin Piaggio 11, 16122 Genova – Tel +39 010 83161

Hotel booking can be made during the online registration procedure.

The total amount due for the hotel accommodation must be settled together with the registration fee.

For special requests (e.g. changing in/out dates or room type), please send a request to the Organizing Secretariat via e-mail.

Hotel rates

NH Collection Marina Rate per night
Double Used as Single (DUS) Superior room € 155,00
NH Genova Centro
Double Used as Single (DUS) standard room € 115,00
Difference for double occupancy  € 20,00

The above rates are intended per room per night including breakfast and VAT.

Guests are kindly asked to settle the City Tax (€ 3,00 per person per night) directly to the hotel reception upon check-out along with any personal extras.

Video recordings (ENG)

24 November – Afternoon session

25 November – Morning session

25 November – Lunch Symposium

Video recordings (ENG)

25 November – Afternoon session

26 November – Morning session


Registration fees (VAT 22% included)
until 30 Sep 2022  from 01 Oct 2022
ISUOG or SIEOG Member  € 400,00  € 450,00
Non member  € 500,00  € 550,00
Physician in training  € 200,00   € 250,00

Fees includes:

Congress attendance

Congress Kit

Coffee break & lunch

Simultaneous translation

Certificate of Attendance

ISUOG Certificate


Symposia Organizzazione Congressi Srl
Piazza Campetto 2/8 – 16123 Genova

Tel. 010 255146 r.a. – Fax 010 2770565

P.IVA 03849570100

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